The focus of this study was to analyze the content, distribution, and comparative genome relationships of 996 chromosome bin-mapped expressed sequence tags accounting for 2266 restriction fragments on the homoeologous group 3 chromosomes of hexaploid wheat. Of these loci, 634, 884, and 748 were mapped on chromosomes 3A, 3B, and 3D, respectively. The individual chromosome bin maps revealed bins with a high density of mapped ESTs in the distal region and bins of low density in the proximal region of the (...) chromosome arms, with the exception of 3DS and 3DL. These distributions were more localized on the higher-resolution group 3 consensus map with intermediate regions of high-mapped-EST density on both chromosome arms. Gene ontology classification of mapped ESTs was not significantly different for homoeologous group 3 chromosomes compared to the other groups. A combined analysis of the individual bin maps using 537 of the mapped ESTs revealed rearrangements between the group 3 chromosomes. Approximately 232 of the consensus mapped ESTs matched sequences on rice chromosome 1 and revealed large- and small-scale differences in gene order. Of the group 3 mapped EST unigenes ∼21 and 32% matched the Arabidopsis coding regions and proteins, respectively, but no chromosome-level gene order conservation was detected. (shrink)

Deep neural networks (DNNs) have had extraordinary successes in classifying photographic images of objects and are often described as the best models of biological vision. This conclusion is largely based on three sets of findings: (1) DNNs are more accurate than any other model in classifying images taken from various datasets, (2) DNNs do the best job in predicting the pattern of human errors in classifying objects taken from various behavioral datasets, and (3) DNNs do the best job in predicting (...) brain signals in response to images taken from various brain datasets (e.g., single cell responses or fMRI data). However, these behavioral and brain datasets do not test hypotheses regarding what features are contributing to good predictions and we show that the predictions may be mediated by DNNs that share little overlap with biological vision. More problematically, we show that DNNs account for almost no results from psychological research. This contradicts the common claim that DNNs are good, let alone the best, models of human object recognition. We argue that theorists interested in developing biologically plausible models of human vision need to direct their attention to explaining psychological findings. More generally, theorists need to build models that explain the results of experiments that manipulate independent variables designed to test hypotheses rather than compete on making the best predictions. We conclude by briefly summarizing various promising modeling approaches that focus on psychological data. (shrink)

On several key issues we agree with the commentators. Perhaps most importantly, everyone seems to agree that psychology has an important role to play in building better models of human vision, and (most) everyone agrees (including us) that deep neural networks (DNNs) will play an important role in modelling human vision going forward. But there are also disagreements about what models are for, how DNN–human correspondences should be evaluated, the value of alternative modelling approaches, and impact of marketing hype in (...) the literature. In our view, these latter issues are contributing to many unjustified claims regarding DNN–human correspondences in vision and other domains of cognition. We explore all these issues in this response. (shrink)

The complex hexaploid wheat genome offers many challenges for genomics research. Expressed sequence tags facilitate the analysis of gene-coding regions and provide a rich source of molecular markers for mapping and comparison with model organisms. The objectives of this study were to construct a high-density EST chromosome bin map of wheat homoeologous group 2 chromosomes to determine the distribution of ESTs, construct a consensus map of group 2 ESTs, investigate synteny, examine patterns of duplication, and assess the colinearity with rice (...) of ESTs assigned to the group 2 consensus bin map. A total of 2600 loci generated from 1110 ESTs were mapped to group 2 chromosomes by Southern hybridization onto wheat aneuploid chromosome and deletion stocks. A consensus map was constructed of 552 ESTs mapping to more than one group 2 chromosome. Regions of high gene density in distal bins and low gene density in proximal bins were found. Two interstitial gene-rich islands flanked by relatively gene-poor regions on both the short and long arms and having good synteny with rice were discovered. The map locations of two ESTs indicated the possible presence of a small pericentric inversion on chromosome 2B. Wheat chromosome group 2 was shown to share syntenous blocks with rice chromosomes 4 and 7. (shrink)

This report describes the rationale, approaches, organization, and resource development leading to a large-scale deletion bin map of the hexaploid wheat genome. Accompanying reports in this issue detail results from chromosome bin-mapping of expressed sequence tags representing genes onto the seven homoeologous chromosome groups and a global analysis of the entire mapped wheat EST data set. Among the resources developed were the first extensive public wheat EST collection. Described are protocols for sequencing, sequence processing, EST nomenclature, and the assembly of (...) ESTs into contigs. These contigs plus singletons were used for selection of distinct sequence motif unigenes. Selected ESTs were rearrayed, validated by 5′ and 3′ sequencing, and amplified for probing a series of wheat aneuploid and deletion stocks. Images and data for all Southern hybridizations were deposited in databases and were used by the coordinators for each of the seven homoeologous chromosome groups to validate the mapping results. Results from this project have established the foundation for future developments in wheat genomics. (shrink)

Ethical mysticism, by S. Coit.--The ethical import of history, by D. S. Muzzey.--The tragic and heroic in life, by W. M. Salter.--Distinctive features of the ethical movement, by A. W. Martin.--Ethical experience as the basis of religious education, by H. Neumann.--"All men are created equal," by G. E. O'Dell.--How far is art an aid to religion? by P. Chubb.--Evolution and the uniqueness of man, by H. J. Bridges.--The spiritual outlook on life, by H. J. Golding.--The ethics of Abu'l Ala al (...) Ma'arri, by N. Schmidt.--Life's unused moral force, by H. Snell.--Is the ideal real? by G. A. Smith.--Some ethical tendencies in the professions, by R. D. Kohn.--On the art of living, by W. Boerner.--The relation of the ethical ideal to social reform, by J. L. Elliott.--Concerning tolerance, by R. F. Dewey.--Ethical culture in Germany after the war, by R. Penzig.--A confession of faith, by S. B. Weston.--"Hearing the witnesses," by J. Gutmann. (shrink)

The consistency strength of the ∑2 priority method is I∑2, yet classical theorems proven by this method have been proved from I∑1. Is there a statement about the structure of the r.e. degrees that can be proved using a ∑2 argument and cannot be proved from I∑1?We rule out statements in the language of partial orderings of the form …[], where is quantifier-free, by showing that the following can be proved in I∑1.If P is any recursive partial ordering with a (...) maximal point d, and a is any nonrecursive incomplete r.e. degree, then P can be embedded into the r.e. degrees by an embedding sending d to a. (shrink)

A ceux qui se montrent désireux de saisir l'épaisseur politique et historique du droit constitutionnel, les différends opposant les corps constitués peuvent apparaître, dans leurs expressions les plus marquées, comme des objets d'étude particulièrement stimulants. En effet, ces conflits peuvent se présenter comme de singuliers laboratoires où devient brusquement visible la texture politique des lois constitutionnelles dont les dispositions sont parfois si fortement tissées d'incertitudes et d'ellipses qu'elles laissent soudain jaillir l'imprévisible. D'une part, le conflit constitutionnel n'est pas une simple (...) controverse constitutionnelle participant généralement d'un processus historique de pacification des différends politiques par le droit : d'autre part, il constitue un conflit politique dont la particularité réside dans le fait que les acteurs s'efforcent d'étayer leur raisonnement par des arguments juridiques tirés d'une lecture de la lettre constitutionnelle, chaque camp accusant la partie adverse d'une mésinterprétation ou d'une violation de ses dispositions. Lors d'une telle crise, mis à l'épreuve de sa propre force, le droit constitutionnel prend toute la mesure de l'indétermination et de la duplicité de ses règles. Qu'ils portent sur l'interprétation ou sur l'application des dispositions constitutionnelles relatives aux modalités d'exercice de la puissance étatique, les différends entre organes constitués peuvent ainsi, dans certaines circonstances, dépasser le stade de la simple controverse pour épouser la forme plus dense du conflit constitutionnel. En effet, quand la difficulté de mettre un terme au différend est telle que les processus de discussion et de délibération codifiés par le droit sont eux-mêmes impuissants à imposer une solution reconnue acceptable par tous les acteurs, le durcissement de la crise peut alors conduire à une situation qu'il est possible de qualifier de conflit constitutionnel. Le présent ouvrage recueille les Actes de la Journée d'études organisée à la Faculté de droit et de science politique de Rennes, le 28 novembre 2008, par le Laboratoire d'Etude du Droit Public de l'université de Rennes 1. (shrink)

Interpretation of this ode has not been very happy in spite of the care lavished upon it by editors obviously determined to extract some sort of consistent sense. That Horace started from Pindar's Olymp. II. is evident enough; when and why, under what stimulus, or for what occasion he wrote is not so clear. The older commentators do not give much help. I believe, however, that in attending to the list of gods, demi-gods, and Roman heroes given in the (...) ode we have a chance of coming somewhere near to an adequate understanding of the poem. (shrink)

‘Shameful are the scars inflicted by the sin of fraternal strife! What has ourunconscionable generation shunned, what abomination left undone? Ourgodless soldiery has held nothing sacred. I pray that Fortune may, on a new anvil, give our blunted swords another shape, to use against Massagetae andArabs!‘.

The fifth poem in Horace's first book of Epistles takes the form of an invitation to Torquatus to attend a dinner which the poet is preparing for that evening, the eveof the Emperor's birthday . The fare will be simple but Horace will see to it that the furnishings, napkins, vessels and plates will be clean and bright and that the company and the seating-plan will be to Torquatus’ taste . Horace will get Butra and Septicius to (...) be there, and Sabinus, too, as long as he is not kept away by a prior dinner engagement or by a girl he'd rather spend the evening with. With Torquatus and Horace, that makes four or five diners, so that there is room for others before the triclinium is full, although there shouldn't be too many; or, as Horace puts it : locus est et pluribus umbris; sed nimis arta premunt olidae conuiuia caprae. (shrink)

The fifth poem in Horace's first book of Epistles takes the form of an invitation to Torquatus to attend a dinner which the poet is preparing for that evening, the eveof the Emperor's birthday. The fare will be simple but Horace will see to it that the furnishings, napkins, vessels and plates will be clean and bright and that the company and the seating-plan will be to Torquatus’ taste. Horace will get Butra and Septicius to be there, (...) and Sabinus, too, as long as he is not kept away by a prior dinner engagement or by a girl he'd rather spend the evening with. With Torquatus and Horace, that makes four or five diners, so that there is room for others before the triclinium is full, although there shouldn't be too many; or, as Horace puts it :locus est et pluribus umbris;sed nimis arta premunt olidae conuiuia caprae. (shrink)

Interpretation of this ode has not been very happy in spite of the care lavished upon it by editors obviously determined to extract some sort of consistent sense. That Horace started from Pindar's Olymp. II. is evident enough; when and why, under what stimulus, or for what occasion he wrote is not so clear. The older commentators do not give much help. I believe, however, that in attending to the list of gods, demi-gods, and Roman heroes given in the (...) ode we have a chance of coming somewhere near to an adequate understanding of the poem. (shrink)

Horace, Janus, and Pighius' Acta In PBSR 54 , 213–28 Andrew Lintott dusts down the fragments of the Acta Urbana published by S. V. Pighius in 1615 and universally supposed today to be a forgery. Lintott himself, after a most learned discussion, concurs, but one senses a wistful longing for the fragments to be genuine. The purpose of this note is to offer another reason why sadly this is unlikely.

Horace, Janus, and Pighius' Acta In PBSR 54, 213–28 Andrew Lintott dusts down the fragments of the Acta Urbana published by S. V. Pighius in 1615 and universally supposed today to be a forgery. Lintott himself, after a most learned discussion, concurs, but one senses a wistful longing for the fragments to be genuine. The purpose of this note is to offer another reason why sadly this is unlikely.

caue, caue; namque in malos asperrimus parata tollo cornua, qualis Lycambae spretus infido gener aut acer hostis Bupalo. an, si quis atra dente me petiuerit, inultus ut flebo puer? Harrison observes that commentators translate ‘“inultus” not “unavenged” but “without taking revenge”, construing it with Horace as the subject of “flebo” and not with “puer”’, and he then asserts ‘This use of “inultus” is wholly unparalleled; the adjective is elsewhere always used passively of persons or objects unavenged and never in (...) the active sense of “unavenging”’. (shrink)

caue, caue; namque in malos asperrimus parata tollo cornua, qualis Lycambae spretus infido gener aut acer hostis Bupalo. an, si quis atra dente me petiuerit, inultus ut flebo puer? Harrison observes that commentators translate ‘“inultus” not “unavenged” but “without taking revenge”, construing it with Horace as the subject of “flebo” and not with “puer”’, and he then asserts ‘This use of “inultus” is wholly unparalleled; the adjective is elsewhere always used passively of persons or objects unavenged and never in (...) the active sense of “unavenging”’. (shrink)

The explanation of the vexed phrase ‘auditor et ultor’ given by Professor E. Fraenkel on p. 349 of his Horace marks a great improvement on previous interpretations. Auditor he translates as ‘pupil’ and ultor he explains as ‘rescuer’ . However I very much doubt whether ultor can in fact bear this meaning. Whatever may be the case with vindex and vindico, I have found no instance of ultor meaning anything but ‘avenger’ or ‘punisher’. Fraenkel takes ‘nobilium scriptorum’ as the (...) Greek poets ‘whose form and spirit he attempted to renew in a different tongue’ 2. (shrink)

This excellent and accessible work includes many major texts in translation: Aristotle's Poetics, Longinus' On Sublimity, Horace's Art of Poetry, Tacitus' Dialogues, and extracts from Plato and Plutarch. Based on the highly praised Ancient Literary Criticism, it contains a new introduction and explanatory notes, and will be of enormous value to students both of Latin and Greek and of literary criticism and theory. ABOUT THE SERIES: For over 100 years Oxford World's Classics has made available the widest range of (...) literature from around the globe. Each affordable volume reflects Oxford's commitment to scholarship, providing the most accurate text plus a wealth of other valuable features, including expert introductions by leading authorities, helpful notes to clarify the text, up-to-date bibliographies for further study, and much more. (shrink)